DHEA and Impaired Glucose Tolerance Clinical and Basic Study

نویسنده

  • Hajime Ueshiba
چکیده

Dehydroepiandrosterone (DHEA) is either secreted directly from the adrenal cortex or is converted from DHEA sulfate (DHEA-S) in the peripheral organs. DHEA and DHEA-S are the most abundant adrenal androgens in blood, however their its physiological roles still remain unclear. Some recent studies have shown that DHEA and DHEA-S exert beneficial effects on conditions such as diabetes mellitus, atherosclerosis, obesity, tumors and osteoporosis (Coleman et al.,1982; Gorden et al.,1988; Cleary,1991). In this chapter, the relationships between DHEA or DHEA-S and diabetes mellitus (DM) or impaired glucose tolerance (IGT) are described.

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تاریخ انتشار 2012